April 2003, Issue 3

Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne [3 + 2] cycloaddition Speers AE, Adam GC, Cravatt BF J Am Chem Soc 2003 Apr 23;125(16):4686-7 A fluorogenic dye activated by the staudinger ligation Lemieux GA, De Graffenried CL, Bertozzi CR J Am Chem Soc 2003 Apr 23;125(16):4708-9 Assembly of cell regulatory systems through protein interaction domains Pawson T, Nash P Science 2003 Apr 18;300(5618):445-52 SELDI-TOF MS for diagnostic proteomics Issaq HJ, Conrads TP, Prieto DA, Tirumalai R, Veenstra TD Anal Chem 2003 Apr 1;75(7):148A-155A Fractionation of cytosolic proteins on an immobilized heparin column Shefcheck K, Yao X, Fenselau C Anal Chem 2003 Apr 1;75(7):1691-8 Elution-modified displacement chromatography coupled with electrospray ionization-MS: on-line detection of trace peptides at low-femtomole level in peptide digests Xiang R, Horvath C, Wilkins JA Anal Chem 2003 Apr 15;75(8):1819-27 Proteomic consequences of a human mitochondrial tRNA mutation beyond the frame of mitochondrial translation Tryoen-Toth P, Richert S, Sohm B, Mine M, Marsac C, Van Dorsselaer A, Leize E, Florentz C J Biol Chem 2003 Apr 24; [epub ahead of print] Biomarkers in drug discovery and development: from target identification through drug marketing Colburn WA J Clin Pharmacol 2003 Apr;43(4):329-41 Directed Evolution of O(6)-Alkylguanine-DNA Alkyltransferase for Efficient Labeling of Fusion Proteins with Small Molecules In Vivo Juillerat A, Gronemeyer T, Keppler A, Gendreizig S, Pick H, Vogel H, Johnsson K Chem Biol 2003 Apr;10(4):313-7 Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14,643 Iida M, Anna CH, Hartis J, Bruno M, Wetmore B, Dubin JR, Sieber S, Bennett L, Cunningham ML, Paules RS, Tomer KB, Houle CD, Merrick AB, Sills RC, Devereux TR Carcinogenesis 2003 Apr;24(4):757-70 Protein and peptide identification: the role of mass spectrometry in proteomics Ashcroft AE Nat Prod Rep 2003 Apr;20(2):202-15 Designing proteins to crystallize through beta-strand pairing Wingren C, Edmundson AB, Borrebaeck CA Protein Eng 2003 Apr;16(4):255-64 The proteome: anno Domini 2002 Righetti PG, Castagna A, Antonucci F, Piubelli C, Cecconi D, Campostrini N, Zanusso G, Monaco S Clin Chem Lab Med 2003 Apr;41(4):425-38 Granular gland transcriptomes in stimulated amphibian skin secretions Chen T, Farragher S, Bjourson AJ, Orr DF, Rao P, Shaw C. Biochem J 2003 Apr 1;371(Pt 1):125-30 CaMBOT: profiling and characterizing calmodulin-binding proteins O'Day DH Cell Signal 2003 Apr;15(4):347-54